| Display Channel | Digital Channel | Call Sign | Network | Nickname | Hours | Notes |
| WGWG | CHARLESTON, SC | |||||
| 02-1 | 34.5005 | WCBD | NBC | "News 2" | ||
| WCBD-TV | CHARLESTON, SC | |||||
| 02-1 | 20.1 | WCBD-HD | NBC | "News 2" | ||
| 02-2 | 20.2 | eCBD-CW | CW+ | "CW14" | ||
| 02-3 | 20.3 | ION | ION | |||
| 02-4 | 20.4 | Laff | Laff | |||
| WTAT-TV | CHARLESTON, SC | |||||
| 04-1 | 17.8 | MeTV | Me-TV | |||
| WGWG | CHARLESTON, SC | |||||
| 04-1 | 34.5001 | WGWG | Me-TV | |||
| WCSC-TV | CHARLESTON, SC | |||||
| 04-2 | 19.8 | WGWGDEC | Catchy Comedy | |||
| WCIV | CHARLESTON, SC | |||||
| 04-3 | 25.6 | Antenna | Antenna TV | |||
| WCBD-TV | CHARLESTON, SC | |||||
| 04-4 | 20.5 | StartTV | Start TV | |||
| WCIV | CHARLESTON, SC | |||||
| 04-5 | 25.7 | H&I | Heroes & Icons | |||
| WCSC-TV | CHARLESTON, SC | |||||
| 05-1 | 19.3 | WCSCDT | CBS | "Live 5" | ||
| WGWG | CHARLESTON, SC | |||||
| 05-1 | 34.5006 | WCSC | CBS | "Live 5" | ||
| WCSC-TV | CHARLESTON, SC | |||||
| 05-2 | 19.4 | WCSCBNC | Bounce TV | |||
| 05-3 | 19.5 | WCSC365 | The365 | |||
| 05-4 | 19.6 | WCSCGRT | Grit | |||
| 05-5 | 19.7 | WCSCDT5 | Quest | |||
| 05-6 | 19.9 | WCSCDT6 | ION Mystery | |||
| 05-7 | 19.10 | PLMSPT | Palmetto Sports & Entertainment | |||
| WITV | CHARLESTON, SC | |||||
| 07-1 | 24.1 | ETV | PBS | "ETV" | ||
| 07-2 | 24.2 | SCC | Create | "SC Channel" | 12a-06p | |
| 07-2 | 24.2 | SCC | PBS Encore | "SC Channel" | 06p-12a | |
| 07-3 | 24.3 | ETVW | PBS Encore | "ETV World" | ||
| 07-4 | 24.4 | ETVK | PBS Kids 24/7 | |||
| WHDC-LD | CHARLESTON, SC | |||||
| 12-1 | 12.3 | WHDC | NewsNet | |||
| 12-2 | 12.4 | SNHtv | Sports News Highlights | |||
| 12-3 | 12.5 | ShopHQ | ShopHQ | |||
| 12-4 | 12.6 | WBPI | Religious | "Watchmen Christian TV" | ||
| 12-5 | 12.7 | Movies | Movies! | |||
| WJWJ-TV | BEAUFORT, SC | |||||
| 16-1 | 32.1 | ETV | PBS | "ETV" | ||
| 16-2 | 32.2 | SCC | Create | "SC Channel" | 12a-06p | |
| 16-2 | 32.2 | SCC | PBS Encore | "SC Channel" | 06p-12a | |
| 16-3 | 32.3 | ETVW | PBS Encore | "ETV World" | ||
| 16-4 | 32.4 | ETVK | PBS Kids 24/7 | |||
| WLCN-CD | CHARLESTON, SC | |||||
| 18-1 | 18.3 | WLCN-HD | CTN | |||
| 18-2 | 18.4 | Lifesty | CTN Lifestyle | |||
| 18-3 | 18.5 | CTNi | CTNi | |||
| 18-4 | 18.6 | WLCN-SD | CTN | |||
| 18-5 | 18.7 | BIZ-TV | Biz TV | |||
| WLOW-LD | Charleston, SC | |||||
| 19-1 | 30.2 | WLOW-LD | Heartland | |||
| 19-2 | 30.4 | RTV | Retro TV | |||
| 19-3 | 30.6 | REVN | Rev'n | |||
| 19-4 | 30.8 | Action | Action Channel | |||
| 19-5 | 30.10 | Family | The Family Channel | |||
| 19-6 | 30.12 | Revival | Revival TV Network | |||
| 19-7 | 30.14 | Insprtn | Inspiration TV | |||
| WBSE-LD | CHARLESTON, SC | |||||
| 20-1 | 27.1001 | WBSE-LD | Jewelry TV | |||
| 20-2 | 27.1002 | WBSE-LD | GET | |||
| 20-3 | 27.1003 | WBSE-LD | Outlaw | |||
| 20-4 | 27.1004 | WBSE-LD | COZI TV | |||
| 20-5 | 27.1005 | WBSE-LD | American Crimes | |||
| 20-6 | 27.1006 | WBSE-LD | Defy TV | |||
| WGWG | CHARLESTON, SC | |||||
| 24-1 | 34.5003 | WTAT | FOX | "Fox 24" | ||
| WTAT-TV | CHARLESTON, SC | |||||
| 24-1 | 17.3 | WTATFOX | FOX | "Fox 24" | ||
| 24-2 | 17.4 | CrimeTV | True Crime Network | |||
| 24-3 | 17.5 | COMET | Comet TV | |||
| 24-4 | 17.6 | Charge! | Charge! | |||
| 24-5 | 17.7 | TBD | TBD | |||
| WAZS-LD | NORTH CHARLESTON, SC | |||||
| 29-1 | 29.2 | WAZS-1 | Quiero TV | |||
| 29-2 | 29.4 | WAZS-2 | Music Videos | "Quiero Musica" | ||
| WJNI-LD | NORTH CHARLESTON, SC | |||||
| 31-1 | 31.2 | WJNI-LD | Estrella TV | |||
| WCIV | CHARLESTON, SC | |||||
| 36-1 | 25.3 | MyTV | MyN | "MyTV Charleston" | ||
| WGWG | CHARLESTON, SC | |||||
| 36-10 | 34.5007 | T2 | T2 | |||
| WCIV | CHARLESTON, SC | |||||
| 36-2 | 25.4 | ABC | ABC | "ABC 4" | ||
| WGWG | CHARLESTON, SC | |||||
| 36-2 | 34.5004 | WCIV | ABC | "ABC 4" | ||
| WCIV | CHARLESTON, SC | |||||
| 36-3 | 25.5 | TheNest | The Nest | |||